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Projects

Ongoing Research

  • Non-Invasive detection of unique molecular signatures in laser induced retinal injuries
  • Identification of the virulence factors involved in the attachment of pseudomonas aeruginosa to contact lenses
  • Molecular characterization of CYP1B1, the causative gene in primary congenital glaucoma
  • Controlled delivery system of the ALK-5 inhibitor SB-505124 for suppression of ocular scarring after glaucoma filtration surgery
  • Expression of circadian clock proteins and clock controlled genes in the ciliary body

Resident Research

  • Surface tension on the ocular surface
  • Aging and Changes in ocular surface tension
  • Lymphatic vessels in leaking blebs following trabeculectomy
  • miRNA in aqueous humor
  • Differential gene expression in conjunctival chalasis

Recently Completed Research

  • Biomarker Detection Following Laser-Induced Retinal and Other Tissue Injury in Primates
  • Biomarkers in Retinal Laser Injury in rabbits
  • Suppression of Ocular Scarring by RNA Interference
  • A Genetic Approach to the Role of CYP1B1 in PCG
  • SENSIMMER Virtual Phaco Trainer for Cataract Surgery sponsored by NIH/ NEI
  • Increasing Geriatrics Expertise in Surgical and Related Medical Specialties,
  • Role of the Interphotoreceptor Retinoid Binding Protein (IRBP) in Primary Congenital Glaucoma
  • Conjunctival Histologic Analysis in Patients with Ocular Hypertension or Open-Angle Glaucoma on Chronic IOP-Lowering Medications

Completed Clinical Trials

  • Peri-ocular pigmentation following topical prostaglandins (Pfizer)
  • Anecortave acetate for the treatment of steroid induced glaucoma and open angle glaucoma
  • Retrospective studies on Macular degeneration (Genentech)
  • Glaucoma management after DSAEK
  • A Dose Volume Study of Anecortave Acetate in patients with Open-Angle Glaucoma or Ocular hypertension