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For patients with major depressive disorder who have not achieved remission through typical treatment methods, Summa Health Behavioral Health Institute provides Spravato™, a nasal spray administered under the supervision of trained healthcare professionals.

More than 16 million adults in the U.S. are affected by depression. While a variety of antidepressant medications help people, about one-third of patients don’t respond to treatment.

Spravato™ nasal spray is a different kind of medication taken with an oral antidepressant for adults with treatment-resistant depression. Approved by the Food and Drug Administration in March 2019, this drug represents the first truly new kind of depression drug since Prozac arrived in 1988.

Patients take Spravato™ twice a week for the first month. During the second month, patients take it once a week. After that, patients will take it once a week or once every two weeks. The oral antidepressant will continue as well.

Spravato™ is prescribed only by specially trained healthcare providers and provided only at certified healthcare facilities, like Summa Health Behavioral Health Institute. After you take Spravato™, a healthcare professional will monitor you for at least two hours during the observation period for possible side effects. You may not be able to drive yourself home.

Serious side effects can include:

  • Sedation and disassociation
  • Risk of abuse or misuse
  • Increased risk of suicidal thoughts and behavior
  • Increased blood pressure
  • Problems with thinking clearly 
  • Bladder problems

Additional side effects include:

  • Dizziness
  • Nausea
  • Spinning sensation
  • Reduced sense of touch and sensation
  • Anxiety
  • Lack of energy
  • Vomiting
  • Feeling drunk

If you’ve struggled with depression and tried two or more antidepressants in your current episode without adequate relief, talk to your doctor to see if you have treatment-resistant depression.

When discussing treatment with Spravato™, be sure to tell your doctor about your complete medical history, including if you have a history of abusing prescription or street drugs or a problem with alcohol. Tell your doctor if you are pregnant or are planning to become pregnant. Your doctor will discuss the possible side effects of Spravato™ so that you can decide together if Spravato™ is right for you.

To learn more or to schedule an appointment, call 234.867.7965.


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If your situation is an emergency, call 911.